Treatments For Generalized Hyperhidrosis

generalized hyperhidrosis

Although there is no known cure for generalized hyperhidrosis, some medications can help alleviate symptoms. Opioids, SSRIs, and Polyneuropathies are some examples. However, if you’re looking for a more permanent solution to your problem, you may want to look into other treatment options. Listed below are the most common treatments for generalized hyperhidrosis. The best way to find relief is to discuss your situation with your doctor.

Secondary hyperhidrosis

While the differential diagnosis of primary and secondary hyperhidrosis in generalized hypohidrosis is not always easy to make, it is important to understand what the underlying cause of sweating is to make an accurate diagnosis. Listed below are the causes of secondary hyperhidrosis. These causes should be kept in mind when assessing patients. The Lakartidningen table is reprinted with permission.

There are several conservative treatments for hyperhidrosis. Some of these include local applications of aluminum chloride, tap water iontophoresis, or intracutaneous injections of botulinum toxin. Other surgical methods include endoscopic sympathectomy, axillary tumescent curettage, and liposuction. Systemic medications are also available. Patients should consider a step-by-step approach, starting with non-invasive treatments.

The treatment for secondary hyperhidrosis is based on the underlying cause of the excessive sweating. A medical condition or medication that has triggered excessive sweating may be the culprit. By addressing the underlying cause, the sweating symptoms will decrease. Oftentimes, the treatment for secondary generalized hyperhidrosis can involve switching or lowering certain medications. To learn more about this condition, talk to your doctor.

If you are experiencing excessive sweating in an area other than the underarms or face, you probably have primary hyperhidrosis. This condition is not caused by heat or exercise and can be embarrassing to suffer from. It is most often treated with prescription antiperspirants. Other medications and even surgery may be needed if the problem is severe. If the treatment does not work, the underlying cause may have to be treated.


Although systemic therapies are often considered unnecessary, they have been shown to have an acceptable adverse effect profile. Systemic treatment is appropriate for patients with generalized, multifocal, and resistant hyperhidrosis. Some of these medications include oral anticholinergics, antihypertensives, and psychoactive agents. Several studies have been conducted to evaluate the effects of systemic therapy on generalized hyperhidrosis.

Benzodiazepines and beta-blockers act on the central nervous system to decrease anxiety. These drugs are effective for episodic or event-driven hyperhidrosis, but they can have negative side effects and can be habit-forming. As a result, patients may need to continue taking their medications to function properly. These drugs should be used with caution in cases where the patient cannot tolerate the sedative effects.

Generalized hyperhidrosis is a chronic condition characterized by excessive perspiration. Approximately 93% of people with hyperhidrosis suffer from the primary form, which usually begins during adolescence. In contrast, 7% of sufferers experience the secondary type of hyperhidrosis. It may also be caused by certain diseases or medical conditions. If you’re wondering if SSRIs are right for you, read on to learn more.

A study of BTX A found that it effectively treats axillary hyperhidrosis. However, the results of this treatment were not consistent across all locations. A major multicentre study reported that BTX A had an excellent effect on axillary hyperhidrosis, but there were other studies that showed a good effect on other areas. In general, the treatment is effective and the effects last for one to four years. There are some side effects of BTX A, including transient dryness.


A combination of opioids, known as buprenorphine-naloxone, has been used to treat people with opioid use disorder in the United States. Compared to methadone, buprenorphine is non-selective and short-acting, and is associated with a reduced risk of overdose. However, it has an associated side effect of hyperhidrosis.

Another class of drugs is the beta-blocker. It acts on the central nervous system and helps reduce the sweating produced by the skin. It is used for episodic and event-driven forms of generalized hyperhidrosis, while some patients have difficulty with sedative effects. Opioids are more frequently prescribed for individuals with severe hyperhidrosis. But there are some risks involved with using these drugs, including the possibility of habit formation.

The mechanism of IT-m agonist-induced sweating is unclear. Some studies suggest that opioids may lead to hypothermia and dysphoria. However, this is unlikely to be the case. There are several factors contributing to delayed onset of this syndrome. The underlying cause may be the opioids, the anesthetic itself, or the patient’s overall health. However, the study suggests that opioids are effective in the treatment of generalized hyperhidrosis.

Lifestyle changes may also help decrease sweating. Personal hygiene is an essential aspect of this disorder. Regularly changing clothes and shoes, shaving and wearing breathable materials can help control sweating. Avoiding activities that increase your body temperature and blood pressure can also help reduce excessive sweating. And remember to relax when you’re sweating. It is important to remember that lifestyle changes are the best cure for hyperhidrosis.


A number of factors can result in the development of polyneuropathies in generalized hyperhidroses, including genetic mutations. In general, the onset of symptoms is often young and gradual, with progressive muscle weakness and atrophy. It typically begins in the feet and legs, then progresses to other parts of the body, including the hands. Symptoms may be apparent at a young age, with hammer toes and high arches. The affected individual usually reports difficulties walking and running, and they may develop painful skin rashes as a result.

In general, the symptoms of polyneuropathy in generalized hyperhidrosis begin in childhood, and some patients may present with trophic changes and limb deformities. Some are progressive, causing hammer toes and claw-like deformities. Others may exhibit deformities of the hands, such as high arches and claw-like deformities. Most are associated with the deficiency of intrinsic foot muscles, and they may be caused by autonomic involvement of the limbs.

Some peripheral nerve disorders, such as diabetic sensorimotor polyneuropathy, may occur in 5% to 10% of the population, with prevalence increasing with age. Diabetes is one of the most common causes of generalized polyneuropathy. This condition affects as much as 66% of patients with type 1 and 2 diabetes, although some studies suggest higher numbers. However, it is important to note that a single case of polyneuropathy can affect 1% of the general population.


Some people suffer from generalized hyperhidrosis, and antiperspirants can help control sweating. However, over-the-counter antiperspirants may not be effective for this condition, and treatment with prescription medications is recommended in those cases. These drugs may be effective in controlling the symptoms of the condition, but some have side effects. Fortunately, antiperspirants for generalized hyperhidrosis don’t contain aluminum chloride, which may cause skin irritation in people with hyperhidrosis. In addition to aluminum chloride, prescription antiperspirants use other active ingredients such as oxybutynin and glycopyrrolate.

The most effective topical antiperspirants for generalized hyperhidrosus are Drysol and iontophoresis. Both of these products contain aluminum salts and work by clogging sweat glands, signaling the body not to produce sweat. The antiperspirant should be applied at bedtime and removed in the morning. If antiperspirants don’t work, use saran wrap. Alternatively, use Drysol once or twice a week until your sweating is under control. If that doesn’t work, try using your regular deodorant on days when Drysol isn’t effective.

Depending on where your sweating occurs, a combination of therapies may be needed to control the condition. If you experience multiple sweating sites, treatment may involve several approaches, including antiperspirants and iontophoresis. In severe cases, multiple treatments may be necessary. A dermatologist can prescribe medications that reduce or eliminate the sweat glands to control the condition. It is also possible that a combination of these methods may be required to cure hyperhidrosis.


Sympathectomy is a surgical procedure in which sympathetic nerves that control sweat glands are interrupted. This procedure can be performed in a minimally invasive manner, using small incisions in the underarm area. Patients should be informed of the risks and benefits of the surgery before undergoing it. Depending on the sympathetic chain section and the patient’s body mass index, compensatory hyperhidrosis may develop, but most patients are satisfied with the outcome.

During the surgery, the surgeon inserts a thin camera attached to a scope through the armpit and into the chest. The surgeon then cuts, clips, or destroys the sweating nerves. The remaining lung is left intact. A small drainage tube is left in the patient for a day after the procedure. The patient may return to work a few days after the surgery. The surgery lasts one to three hours.

Patients with facial hyperhidrosis may benefit from sympathectomy as well. The procedure is very effective for patients who suffer from blushing. Because sympathectomy is performed at a high level, it involves a higher risk of CH than other locations. Patients must be evaluated carefully for this surgery and be informed about the risks and benefits of the procedure prior to going under the knife. If the patient is eligible, sympathectomy can lead to complete relief.